Established in 1996 and inspired by the historical, geographical and human cultures of the Loire Valley, LE STUDIUM Loire Valley Institute for Advanced Studies covers all research domains in one global initiative aiming at boosting international scientific exchanges in the Centre-Val de Loire region and creating a dynamic scientific community that supports research and innovation. Headquartered in the city centre of Orleans, right next to the Orléans’ cathedral, in the former episcopal palace built between 1635 and 1641, locally known as the Hôtel Dupanloup and which served of residence to the bishops of Orléans until 1905, the institute displays exceptional facilities. Across a series of different research programmes and an annual call for applications, the Smart Loire Valley Programme, LE STUDIUM attracts, selects and welcomes experienced international researchers into public and private regional laboratories for long-term residencies. The organisation of scientific events and networking actions enable the development of sustainable international collaborations and scientific interdisciplinary exchanges. LE STUDIUM Loire Valley Institute for Advanced Studies offers international invited research fellows and professors an intellectual and human space favouring interdisciplinary exchanges and debates ; it is guided by the three necessary conditions required for a creative activity, namely Curiosity, Imagination and Intuition. The development of human capital for research, development and innovation is at the heart of its mission.