Derived from a traditional Cook Islands treatment for bone and soft tissue injuries. This was developed with permission and equity partnership with the traditional leaders of the Cook Islands the Koutu Nui and has been recognised and supported by the UN and the Cook Islands Government. The research and development demonstrated that the topical application of these plant extracts influenced the biology of healing bone, the details of which are contained in the PhD completed and published at UNSW under the supervision of Professor W R Walsh (Bill) who is a recognised world expert in bone regeneration and orthopaedic research. The extract and its effects have been awarded patents in the major markets of the world, including in China and India where challenges to the use of plants were raised on the basis of their own traditional medicines, challenges that were successfully rebutted and patents awarded