The Penn Interdisciplinary Network for Scientists Promoting Inclusion, Retention, and Equity (Penn INSPIRE) is a trainee-led coalition advocating for scientists and physicians historically marginalized and excluded in STEM across all degree and professional levels. We strive to create inclusive platforms, advocating for and implementing initiatives to empower individuals at the margins of Academia, with diverse gender identities, backgrounds, ethnicities, and sexual orientations. We are dedicated to expanding opportunities for current graduate and medical students, as well as postdoctoral fellows in the Penn community through outreach, fundraising, intrapreneurship, and media engagement initiatives.